NS3 Protease from Hepatitis C Virus: Biophysical Studies on an Intrinsically Disordered Protein Domain

The nonstructural protein 3 (NS3) from the hepatitis C virus (HCV) is responsible for processing the non-structural region of the viral precursor polyprotein in infected hepatic cells. NS3 protease activity, located at the N-terminal domain, is a zinc-dependent serine protease. A zinc ion, required...

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Detalles Bibliográficos
Autores principales: Vega, Sonia, Neira, Jose L., Marcuello, Carlos, Lostao, Anabel, Abian, Olga, Velazquez-Campoy, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742187/
https://www.ncbi.nlm.nih.gov/pubmed/23803659
http://dx.doi.org/10.3390/ijms140713282