Presence of proNGF-Sortilin Signaling Complex in Nigral Dopamine Neurons and Its Variation in Relation to Aging, Lactacystin and 6-OHDA Insults

Growing evidence has shown that proNGF-p75NTR-sortilin signaling might be a crucial factor in neurodegeneration, but it remains unclear if it may function in nigral neurons under aging and disease. The purpose of this study is to examine and quantify proNGF and sortilin expression in the substantia...

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Detalles Bibliográficos
Autores principales: Xia, Yi, Chen, Bei-Yu, Sun, Xiao-Long, Duan, Li, Gao, Guo-Dong, Wang, Jing-Jie, Yung, Ken Kam-Lin, Chen, Liang-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742233/
https://www.ncbi.nlm.nih.gov/pubmed/23880857
http://dx.doi.org/10.3390/ijms140714085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742233/
https://www.ncbi.nlm.nih.gov/pubmed/23880857
http://dx.doi.org/10.3390/ijms140714085

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