Novel Hybrid Virtual Screening Protocol Based on Molecular Docking and Structure-Based Pharmacophore for Discovery of Methionyl-tRNA Synthetase Inhibitors as Antibacterial Agents

Methione tRNA synthetase (MetRS) is an essential enzyme involved in protein biosynthesis in all living organisms and is a potential antibacterial target. In the current study, the structure-based pharmacophore (SBP)-guided method has been suggested to generate a comprehensive pharmacophore of MetRS...

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Detalles Bibliográficos
Autores principales: Liu, Chi, He, Gu, Jiang, Qinglin, Han, Bo, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742241/
https://www.ncbi.nlm.nih.gov/pubmed/23839093
http://dx.doi.org/10.3390/ijms140714225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742241/
https://www.ncbi.nlm.nih.gov/pubmed/23839093
http://dx.doi.org/10.3390/ijms140714225

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