Effect of Amphipathic HIV Fusion Inhibitor Peptides on POPC and POPC/Cholesterol Membrane Properties: A Molecular Simulation Study

T-20 and T-1249 fusion inhibitor peptides were shown to interact with 1-palmitoyl-2-oleyl-phosphatidylcholine (POPC) (liquid disordered, ld) and POPC/cholesterol (1:1) (POPC/Chol) (liquid ordered, lo) bilayers, and they do so to different extents. Although they both possess a tryptophan-rich domain...

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Detalles Bibliográficos
Autores principales: Martins do Canto, António M. T., Palace Carvalho, Alfredo J., Prates Ramalho, João P., Loura, Luís M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742270/
https://www.ncbi.nlm.nih.gov/pubmed/23860208
http://dx.doi.org/10.3390/ijms140714724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742270/
https://www.ncbi.nlm.nih.gov/pubmed/23860208
http://dx.doi.org/10.3390/ijms140714724

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