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SnoRNA U50 Levels Are Regulated by Cell Proliferation and rRNA Transcription

rRNA post transcriptional modifications play a role in cancer development by affecting ribosomal function. In particular, the snoRNA U50, mediating the methylation of C2848 in 28S rRNA, has been suggested as a potential tumor suppressor-like gene playing a role in breast and prostate cancers and B-c...

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Detalles Bibliográficos
Autores principales: Pacilli, Annalisa, Ceccarelli, Claudio, Treré, Davide, Montanaro, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742280/
https://www.ncbi.nlm.nih.gov/pubmed/23867608
http://dx.doi.org/10.3390/ijms140714923