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Cytosolic Phospholipase A(2)α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation

The role of Group IVA cytosolic phospholipase A(2) (cPLA(2)α) activation in regulating macrophage transcriptional responses to Candida albicans infection was investigated. cPLA(2)α releases arachidonic acid for the production of eicosanoids. In mouse resident peritoneal macrophages, prostacyclin, pr...

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Detalles Bibliográficos
Autores principales: Suram, Saritha, Silveira, Lori J., Mahaffey, Spencer, Brown, Gordon D., Bonventre, Joseph V., Williams, David L., Gow, Neil A. R., Bratton, Donna L., Murphy, Robert C., Leslie, Christina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742295/
https://www.ncbi.nlm.nih.gov/pubmed/23950842
http://dx.doi.org/10.1371/journal.pone.0069002