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Cytosolic Phospholipase A(2)α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation
The role of Group IVA cytosolic phospholipase A(2) (cPLA(2)α) activation in regulating macrophage transcriptional responses to Candida albicans infection was investigated. cPLA(2)α releases arachidonic acid for the production of eicosanoids. In mouse resident peritoneal macrophages, prostacyclin, pr...
Autores principales: | Suram, Saritha, Silveira, Lori J., Mahaffey, Spencer, Brown, Gordon D., Bonventre, Joseph V., Williams, David L., Gow, Neil A. R., Bratton, Donna L., Murphy, Robert C., Leslie, Christina C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742295/ https://www.ncbi.nlm.nih.gov/pubmed/23950842 http://dx.doi.org/10.1371/journal.pone.0069002 |
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