MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4

MDM2 Binding Protein (MTBP) has been implicated in cancer progression. Here we demonstrate one mechanism by which MTBP inhibits cancer metastasis. Overexpression of MTBP in human osteosarcoma cell lines lacking wild-type p53 did not alter primary tumor growth in mice but significantly inhibited meta...

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Detalles Bibliográficos
Autores principales: Agarwal, Neeraj, Adhikari, Amit S., Iyer, Swathi V., Hekmatdoost, Kevon, Welch, Danny R., Iwakuma, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742333/
https://www.ncbi.nlm.nih.gov/pubmed/22370640
http://dx.doi.org/10.1038/onc.2012.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742333/
https://www.ncbi.nlm.nih.gov/pubmed/22370640
http://dx.doi.org/10.1038/onc.2012.69

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