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Influence of rs1080985 single nucleotide polymorphism of the CYP2D6 gene on response to treatment with donepezil in patients with alzheimer’s disease

BACKGROUND: Recent data indicate that the rs1080985 single nucleotide polymorphism of the cytochrome P450 (CYP) 2D6 gene may affect the response to treatment with donepezil in patients with Alzheimer’s disease. There is also evidence that the common apolipoprotein E (APOE) polymorphism may affect th...

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Detalles Bibliográficos
Autores principales: Klimkowicz-Mrowiec, Aleksandra, Wolkow, Pawel, Sado, Malgorzata, Dziubek, ANNA, Pera, Joanna, Dziedzic, Tomasz, Szczudlik, Andrzej, Slowik, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742350/
https://www.ncbi.nlm.nih.gov/pubmed/23950644
http://dx.doi.org/10.2147/NDT.S46689