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Hereditary Disorders with Defective Repair of UV-Induced DNA Damage

Nucleotide excision repair (NER) is an essential system for correcting ultraviolet (UV)—induced DNA damage. Lesions remaining in DNA due to reduced capacity of NER may result in cellular death, premature aging, mutagenesis and carcinogenesis of the skin. So, NER is an important protection against th...

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Detalles Bibliográficos
Autor principal: Moriwaki, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742358/
https://www.ncbi.nlm.nih.gov/pubmed/23966815
http://dx.doi.org/10.4137/JCM.S10730