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Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer

PURPOSE: Advanced thyroid cancer responds poorly to most therapies. New therapies and combinations are needed. The aim of this study was to examine both in vitro and in vivo activity of two relatively new histone deacetylase inhibitors (HDACIs), belinostat and panobinostat, and a variety of tyrosine...

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Detalles Bibliográficos
Autores principales: Chan, Daniel, Zheng, Yun, Tyner, Jeffrey W., Chng, Wee Joo, Chien, Wen Wen, Gery, Sigal, Leong, Geraldine, Braunstein, Glenn D., Koeffler, H. Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742422/
https://www.ncbi.nlm.nih.gov/pubmed/23824064
http://dx.doi.org/10.1007/s00432-013-1465-6