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How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals
The development of the embryonic brain critically depends on successfully completing cranial neural tube closure (NTC). Failure to properly close the neural tube results in significant and potentially lethal neural tube defects (NTDs). We believe these malformations are caused by disruptions in norm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742426/ https://www.ncbi.nlm.nih.gov/pubmed/23242429 http://dx.doi.org/10.1007/s00018-012-1227-7 |