Reduced Juvenile Long-Term Depression in Tuberous Sclerosis Complex Is Mitigated in Adults by Compensatory Recruitment of mGluR5 and Erk Signaling

Tuberous sclerosis complex (TSC) is a multisystem genetic disease that manifests with mental retardation, tumor formation, autism, and epilepsy. Heightened signaling through the mammalian target of rapamycin (mTOR) pathway is involved in TSC pathology, however it remains unclear how other signaling...

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Detalles Bibliográficos
Autores principales: Potter, Wyatt B., Basu, Trina, O'Riordan, Kenneth J., Kirchner, Allison, Rutecki, Paul, Burger, Corinna, Roopra, Avtar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742461/
https://www.ncbi.nlm.nih.gov/pubmed/23966835
http://dx.doi.org/10.1371/journal.pbio.1001627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742461/
https://www.ncbi.nlm.nih.gov/pubmed/23966835
http://dx.doi.org/10.1371/journal.pbio.1001627

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