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Gene expression profiling of the DNMT3A R882 mutation in acute leukemia

DNA methyltransferase 3A (DNMT3A) is one of two human de novo DNA methyltransferases essential for the regulation of gene expression. DNMT3A mutations and deletions have been previously observed in acute myeloid leukemia (AML), myelodysplastic sydromes and myeloproliferative neoplasms. However, the...

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Detalles Bibliográficos
Autores principales: HUANG, XIANGNAN, MA, DAOXIN, DONG, WENHAO, LI, PENG, LU, TING, HE, NA, TIAN, TIAN, LIU, NA, DU, YAHUI, JI, CHUNYAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742503/
https://www.ncbi.nlm.nih.gov/pubmed/23946816
http://dx.doi.org/10.3892/ol.2013.1347