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Camkii-Mediated Phosphorylation Regulates Distributions of Syngap-α1 and –α2 at the Postsynaptic Density

SynGAP, a protein abundant at the postsynaptic density (PSD) of glutamatergic neurons, is known to modulate synaptic strength by regulating the incorporation of AMPA receptors at the synapse. Two isoforms of SynGAP, α1 and α2, which differ in their C-termini, have opposing effects on synaptic streng...

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Detalles Bibliográficos
Autores principales: Yang, Yijung, Tao-Cheng, Jung-Hwa, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742523/
https://www.ncbi.nlm.nih.gov/pubmed/23967245
http://dx.doi.org/10.1371/journal.pone.0071795