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FERM Domain Containing Protein 7 Interacts with the Rho GDP Dissociation Inhibitor and Specifically Activates Rac1 Signaling

The FERM domain containing protein 7 gene (FRMD7) associated with the X-linked disorder idiopathic congenital nystagmus (ICN) is involved in the regulation of neurite elongation during neuronal development. Members of the Rho family of small G-proteins (Rho GTPases) are key regulators of the actin c...

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Detalles Bibliográficos
Autores principales: Pu, Jiali, Mao, Yanfang, Lei, Xiaoguang, Yan, Yaping, Lu, Xiaoxiong, Tian, Jun, Yin, Xinzhen, Zhao, Guohua, Zhang, Baorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742540/
https://www.ncbi.nlm.nih.gov/pubmed/23967341
http://dx.doi.org/10.1371/journal.pone.0073108