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Trk B signaling in dopamine 1 receptor neurons regulates food intake and body weight

OBJECTIVE: Loss of BDNF-TrkB signaling results in obesity in both humans and mice; however, the neural circuit that mediates this effect is unknown. We tested the role of TrkB signaling dopamine-1 receptor expressing neurons in body weight regulation. DESIGN AND METHODS: Mice with a floxed allele of...

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Detalles Bibliográficos
Autores principales: Mason, Brittany L., Lobo, Mary Kay, Parada, Luis F., Lutter, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742719/
https://www.ncbi.nlm.nih.gov/pubmed/23512795
http://dx.doi.org/10.1002/oby.20382