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An In Silico Analysis of Troponin I Mutations in Hypertrophic Cardiomyopathy of Indian Origin
Hypertrophic Cardiomyopathy (HCM) is an autosomal dominant disorder of the myocardium which is hypertrophied resulting in arrhythmias and heart failure leading to sudden cardiac death (SCD). Several sarcomeric proteins and modifier genes have been implicated in this disease. Troponin I, being a part...
Autores principales: | Ramachandran, Gayatri, Kumar, Manoj, Selvi Rani, Deepa, Annanthapur, Venkateshwari, Calambur, Narasimhan, Nallari, Pratibha, Kaur, Punit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742764/ https://www.ncbi.nlm.nih.gov/pubmed/23967088 http://dx.doi.org/10.1371/journal.pone.0070704 |
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