STAT3 Regulates MMP3 in Heme-Induced Endothelial Cell Apoptosis

BACKGROUND: We have previously reported that free Heme generated during experimental cerebral malaria (ECM) in mice, is central to the pathogenesis of fatal ECM. Heme-induced up-regulation of STAT3 and CXCL10 promotes whereas up-regulation of HO-1 prevents brain tissue damage in ECM. We have previou...

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Detalles Bibliográficos
Autores principales: Liu, Mingli, Wilson, Nana O., Hibbert, Jacqueline M., Stiles, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742773/
https://www.ncbi.nlm.nih.gov/pubmed/23967200
http://dx.doi.org/10.1371/journal.pone.0071366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742773/
https://www.ncbi.nlm.nih.gov/pubmed/23967200
http://dx.doi.org/10.1371/journal.pone.0071366

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