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n→π* Interactions of Amides and Thioamides: Implications for Protein Stability

[Image: see text] Carbonyl–carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor–acceptor interactio...

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Detalles Bibliográficos
Autores principales: Newberry, Robert W., VanVeller, Brett, Guzei, Ilia A., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742804/
https://www.ncbi.nlm.nih.gov/pubmed/23663100
http://dx.doi.org/10.1021/ja4033583