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Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations

The persistence leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) despite tyrosine kinase inhibition (TKI) may explain relapse after TKI withdrawal. Here we performed genome-wide transcriptome analysis of highly refined CML and normal stem and progenitor cell populations to identify novel...

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Detalles Bibliográficos
Autores principales: Gerber, Jonathan M., Gucwa, Jessica L., Esopi, David, Gurel, Meltem, Haffner, Michael C., Vala, Milada, Nelson, William G., Jones, Richard J., Yegnasubramanian, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742832/
https://www.ncbi.nlm.nih.gov/pubmed/23651669