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Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations
The persistence leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) despite tyrosine kinase inhibition (TKI) may explain relapse after TKI withdrawal. Here we performed genome-wide transcriptome analysis of highly refined CML and normal stem and progenitor cell populations to identify novel...
Autores principales: | Gerber, Jonathan M., Gucwa, Jessica L., Esopi, David, Gurel, Meltem, Haffner, Michael C., Vala, Milada, Nelson, William G., Jones, Richard J., Yegnasubramanian, Srinivasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742832/ https://www.ncbi.nlm.nih.gov/pubmed/23651669 |
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