Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma

T-oligo, an 11-base oligonucleotide homologous to the 3'-telomeric overhang, is a novel, potent therapeutic modality in melanoma and multiple other tumor types. T-oligo is proposed to function in a manner similar to experimental disruption of the telomere overhang and induces DNA damage respons...

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Detalles Bibliográficos
Autores principales: Pitman, Ryan T, Wojdyla, Luke, Puri, Neelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742836/
https://www.ncbi.nlm.nih.gov/pubmed/23800953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742836/
https://www.ncbi.nlm.nih.gov/pubmed/23800953

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