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Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics
It is well established that only estrogen receptor (ER)-positive tumors benefit from hormonal therapies. We hypothesized that a subgroup of breast cancer patients expresses estrogen receptor α (ERα), but fails to respond to hormonal therapy due to the expression of a non-functional receptor. We anal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742961/ https://www.ncbi.nlm.nih.gov/pubmed/23912957 http://dx.doi.org/10.1007/s10549-013-2648-1 |