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Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics

It is well established that only estrogen receptor (ER)-positive tumors benefit from hormonal therapies. We hypothesized that a subgroup of breast cancer patients expresses estrogen receptor α (ERα), but fails to respond to hormonal therapy due to the expression of a non-functional receptor. We anal...

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Detalles Bibliográficos
Autores principales:	Groenendijk, Floris H., Zwart, Wilbert, Floore, Arno, Akbari, Stephanie, Bernards, Rene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742961/ https://www.ncbi.nlm.nih.gov/pubmed/23912957 http://dx.doi.org/10.1007/s10549-013-2648-1

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