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Insights into the Acid–Base Properties of Pt(IV)–Diazidodiam(m)inedihyroxido Complexes from Multinuclear NMR Spectroscopy

Platinum(IV) am(m)ine complexes are of interest as potential anticancer pro-drugs, but there are few reports of their acid–base properties. We have studied the acid–base properties of three photoactivatable anticancer platinum(IV)-diazidodiam(m)ine complexes (cis,trans,cis-[Pt(IV)(N(3))(2)(OH)(2)(NH...

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Detalles Bibliográficos
Autores principales: Ronconi, Luca, Pizarro, Ana M, McQuitty, Ruth J, Sadler, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743210/
https://www.ncbi.nlm.nih.gov/pubmed/21922567
http://dx.doi.org/10.1002/chem.201002792