Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell of origin model for prostate cancer heterogeneity

A key issue in cancer biology is whether oncogenic transformation of different cell types of origin within an adult tissue gives rise to distinct tumor subtypes that differ in their prognosis and/or treatment response. We now show that initiation of prostate tumors in basal or luminal epithelial cel...

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Detalles Bibliográficos
Autores principales: Wang, Zhu A., Mitrofanova, Antonina, Bergren, Sarah K., Abate-Shen, Cory, Cardiff, Robert D., Califano, Andrea, Shen, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743266/
https://www.ncbi.nlm.nih.gov/pubmed/23434823
http://dx.doi.org/10.1038/ncb2697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743266/
https://www.ncbi.nlm.nih.gov/pubmed/23434823
http://dx.doi.org/10.1038/ncb2697

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