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A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012

BACKGROUND: Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of action potentials, 2) and action on synaptic tr...

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Detalles Bibliográficos
Autores principales: Tolou-Ghamari, Zahra, Zare, Mohammad, Habibabadi, Jafar Mehvari, Najafi, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743329/
https://www.ncbi.nlm.nih.gov/pubmed/23961295