The Keap1/Nrf2 Protein Axis Plays a Role in Osteoclast Differentiation by Regulating Intracellular Reactive Oxygen Species Signaling

Reactive oxygen species (ROS) act as intracellular signaling molecules in the regulation of receptor activator of nuclear factor-κB ligand (RANKL)-dependent osteoclast differentiation, but they also have cytotoxic effects that include peroxidation of lipids and oxidative damage to proteins and DNA....

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Detalles Bibliográficos
Autores principales: Kanzaki, Hiroyuki, Shinohara, Fumiaki, Kajiya, Mikihito, Kodama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743476/
https://www.ncbi.nlm.nih.gov/pubmed/23801334
http://dx.doi.org/10.1074/jbc.M113.478545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743476/
https://www.ncbi.nlm.nih.gov/pubmed/23801334
http://dx.doi.org/10.1074/jbc.M113.478545

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