Developing therapeutic approaches for metachromatic leukodystrophy

Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal disorder caused by the deficiency of arylsulfatase A (ASA), resulting in impaired degradation of sulfatide, an essential sphingolipid of myelin. The clinical manifestations of MLD are characterized by progressive demyelination an...

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Detalles Bibliográficos
Autores principales: Patil, Shilpa A, Maegawa, Gustavo HB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743609/
https://www.ncbi.nlm.nih.gov/pubmed/23966770
http://dx.doi.org/10.2147/DDDT.S15467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743609/
https://www.ncbi.nlm.nih.gov/pubmed/23966770
http://dx.doi.org/10.2147/DDDT.S15467

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