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Developing therapeutic approaches for metachromatic leukodystrophy

Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal disorder caused by the deficiency of arylsulfatase A (ASA), resulting in impaired degradation of sulfatide, an essential sphingolipid of myelin. The clinical manifestations of MLD are characterized by progressive demyelination an...

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Detalles Bibliográficos
Autores principales:	Patil, Shilpa A, Maegawa, Gustavo HB
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743609/ https://www.ncbi.nlm.nih.gov/pubmed/23966770 http://dx.doi.org/10.2147/DDDT.S15467

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