Self-microemulsifying drug delivery system for improved oral bioavailability of oleanolic acid: design and evaluation

Oleanolic acid is a poorly water-soluble drug with low oral bioavailability. A self-microemulsifying drug delivery system (SMEDDS) has been developed to enhance the solubility and oral bioavailability of oleanolic acid. The formulation design was optimized by solubility assay, compatibility tests, a...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Huang, Xin, Dou, Jinfeng, Zhai, Guangxi, Su, Lequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743642/
https://www.ncbi.nlm.nih.gov/pubmed/23966781
http://dx.doi.org/10.2147/IJN.S47510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743642/
https://www.ncbi.nlm.nih.gov/pubmed/23966781
http://dx.doi.org/10.2147/IJN.S47510

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