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Cisplatin-incorporated nanoparticles of poly(acrylic acid-co-methyl methacrylate) copolymer
BACKGROUND: Although cisplatin is extensively used in the clinical field, its intrinsic toxicity limits its clinical use. We investigated nanoparticle formations of poly(acrylic acid-co-methyl methacrylate) (PAA-MMA) incorporating cisplatin and their antitumor activity in vitro and in vivo. METHODS:...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743654/ https://www.ncbi.nlm.nih.gov/pubmed/23966778 http://dx.doi.org/10.2147/IJN.S48367 |