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Cisplatin-incorporated nanoparticles of poly(acrylic acid-co-methyl methacrylate) copolymer

BACKGROUND: Although cisplatin is extensively used in the clinical field, its intrinsic toxicity limits its clinical use. We investigated nanoparticle formations of poly(acrylic acid-co-methyl methacrylate) (PAA-MMA) incorporating cisplatin and their antitumor activity in vitro and in vivo. METHODS:...

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Detalles Bibliográficos
Autores principales:	Lee, Kyung Dong, Jeong, Young-Il, Kim, Da Hye, Lim, Gyun-Taek, Choi, Ki-Choon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743654/ https://www.ncbi.nlm.nih.gov/pubmed/23966778 http://dx.doi.org/10.2147/IJN.S48367

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