Nurr1 Represses Tyrosine Hydroxylase Expression via SIRT1 in Human Neural Stem Cells

Nurr1 is an orphan nuclear receptor best known for its essential role in the development and maintenance of midbrain dopaminergic (DA) neurons. During DA neurogenesis, Nurr1 directly targets human tyrosine hydroxylase (hTH). Here we investigated this targeting to identify the molecular mechanisms by...

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Detalles Bibliográficos
Autores principales: Kim, Tae Eun, Seo, Ji Sun, Yang, Jae Won, Kim, Min Woong, Kausar, Rukhsana, Joe, Eunhye, Kim, Bo Yeon, Lee, Myung Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743743/
https://www.ncbi.nlm.nih.gov/pubmed/23977047
http://dx.doi.org/10.1371/journal.pone.0071469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743743/
https://www.ncbi.nlm.nih.gov/pubmed/23977047
http://dx.doi.org/10.1371/journal.pone.0071469

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