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Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction

This study is the first to demonstrate that shizukaol D, a natural compound isolated from Chloranthus japonicus , can activate AMP- activated protein kinase (AMPK), a key sensor and regulator of intracellular energy metabolism, leading to a decrease in triglyceride and cholesterol levels in HepG2 ce...

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Detalles Bibliográficos
Autores principales: Hu, Rongkuan, Yan, Huan, Hao, Xiaojiang, Liu, Haiyang, Wu, Jiarui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743771/
https://www.ncbi.nlm.nih.gov/pubmed/23967345
http://dx.doi.org/10.1371/journal.pone.0073527