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Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction
This study is the first to demonstrate that shizukaol D, a natural compound isolated from Chloranthus japonicus , can activate AMP- activated protein kinase (AMPK), a key sensor and regulator of intracellular energy metabolism, leading to a decrease in triglyceride and cholesterol levels in HepG2 ce...
Autores principales: | Hu, Rongkuan, Yan, Huan, Hao, Xiaojiang, Liu, Haiyang, Wu, Jiarui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743771/ https://www.ncbi.nlm.nih.gov/pubmed/23967345 http://dx.doi.org/10.1371/journal.pone.0073527 |
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