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Cis Association of Galectin-9 with Tim-3 Differentially Regulates IL-12/IL-23 Expressions in Monocytes via TLR Signaling

Human monocytes/macrophages (M/M(Ф)) of the innate immunity sense and respond to microbial products via specific receptor coupling with stimulatory (such as TLR) and inhibitory (such as Tim-3) receptors. Current models imply that Tim-3 expression on M/M(Ø) can deliver negative signaling to TLR-media...

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Detalles Bibliográficos
Autores principales: Ma, Cheng J., Li, Guang Y., Cheng, Yong Q., Wang, Jia M., Ying, Ruo S., Shi, Lei, Wu, Xiao Y., Niki, Toshiro, Hirashima, Mitsumi, Li, Chuan F., Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743775/
https://www.ncbi.nlm.nih.gov/pubmed/23967307
http://dx.doi.org/10.1371/journal.pone.0072488