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Cis Association of Galectin-9 with Tim-3 Differentially Regulates IL-12/IL-23 Expressions in Monocytes via TLR Signaling
Human monocytes/macrophages (M/M(Ф)) of the innate immunity sense and respond to microbial products via specific receptor coupling with stimulatory (such as TLR) and inhibitory (such as Tim-3) receptors. Current models imply that Tim-3 expression on M/M(Ø) can deliver negative signaling to TLR-media...
Autores principales: | Ma, Cheng J., Li, Guang Y., Cheng, Yong Q., Wang, Jia M., Ying, Ruo S., Shi, Lei, Wu, Xiao Y., Niki, Toshiro, Hirashima, Mitsumi, Li, Chuan F., Moorman, Jonathan P., Yao, Zhi Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743775/ https://www.ncbi.nlm.nih.gov/pubmed/23967307 http://dx.doi.org/10.1371/journal.pone.0072488 |
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