Bruton’s Tyrosine Kinase Mediates the Synergistic Signalling between TLR9 and the B Cell Receptor by Regulating Calcium and Calmodulin

B cells signal through both the B cell receptor (BCR) which binds antigens and Toll-like receptors (TLRs) including TLR9 which recognises CpG DNA. Activation of TLR9 synergises with BCR signalling when the BCR and TLR9 co-localise within an auto-phagosome-like compartment. Here we report that Bruton...

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Detalles Bibliográficos
Autores principales: Kenny, Elaine F., Quinn, Susan R., Doyle, Sarah L., Vink, Paul M., van Eenennaam, Hans, O’Neill, Luke A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743783/
https://www.ncbi.nlm.nih.gov/pubmed/23967355
http://dx.doi.org/10.1371/journal.pone.0074103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743783/
https://www.ncbi.nlm.nih.gov/pubmed/23967355
http://dx.doi.org/10.1371/journal.pone.0074103

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