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Integration of Steady-State and Temporal Gene Expression Data for the Inference of Gene Regulatory Networks
We develop a new regression algorithm, cMIKANA, for inference of gene regulatory networks from combinations of steady-state and time-series gene expression data. Using simulated gene expression datasets to assess the accuracy of reconstructing gene regulatory networks, we show that steady-state and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743784/ https://www.ncbi.nlm.nih.gov/pubmed/23967277 http://dx.doi.org/10.1371/journal.pone.0072103 |