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Structural Basis of α-Catenin Recognition by EspB from Enterohaemorrhagic E. coli Based on Hybrid Strategy Using Low-Resolution Structural and Protein Dissection

Enterohaemorrhagic E. coli (EHEC) induces actin reorganization of host cells by injecting various effectors into host cytosol through type III secretion systems. EspB is the natively partially folded EHEC effector which binds to host α-catenin to promote the actin bundling. However, its structural b...

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Detalles Bibliográficos
Autores principales: Hamaguchi, Mitsuhide, Kamikubo, Hironari, Suzuki, Kayo N., Hagihara, Yoshihisa, Yanagihara, Itaru, Sakata, Ikuhiro, Kataoka, Mikio, Hamada, Daizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743801/
https://www.ncbi.nlm.nih.gov/pubmed/23967227
http://dx.doi.org/10.1371/journal.pone.0071618