Loss of the Anorexic Response to Systemic 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside Administration Despite Reducing Hypothalamic AMP-Activated Protein Kinase Phosphorylation in Insulin-Deficient Rats

This study tested whether chronic systemic administration of 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) could attenuate hyperphagia, reduce lean and fat mass losses, and improve whole-body energy homeostasis in insulin-deficient rats. Male Wistar rats were first rendered diabetic th...

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Detalles Bibliográficos
Autores principales: Vitzel, Kaio F., Bikopoulos, George, Hung, Steven, Curi, Rui, Ceddia, Rolando B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743807/
https://www.ncbi.nlm.nih.gov/pubmed/23967267
http://dx.doi.org/10.1371/journal.pone.0071944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743807/
https://www.ncbi.nlm.nih.gov/pubmed/23967267
http://dx.doi.org/10.1371/journal.pone.0071944

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