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Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes

BACKGROUND: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear. OBJECTIVES: This study evaluated the interaction between single nucleotide polymorphisms (SNPs) in genes associated w...

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Detalles Bibliográficos
Autores principales: Pan, Wen-Chi, Kile, Molly L., Seow, Wei Jie, Lin, Xihong, Quamruzzaman, Quazi, Rahman, Mahmuder, Mahiuddin, Golam, Mostofa, Golam, Lu, Quan, Christiani, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743824/
https://www.ncbi.nlm.nih.gov/pubmed/23967108
http://dx.doi.org/10.1371/journal.pone.0070792