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Novel Synthetic Monoketone Transmute Radiation-Triggered NFκB-Dependent TNFα Cross-Signaling Feedback Maintained NFκB and Favors Neuroblastoma Regression

Recently, we demonstrated that radiation (IR) instigates the occurrence of a NFκB-TNFα feedback cycle which sustains persistent NFκB activation in neuroblastoma (NB) cells and favors survival advantage and clonal expansion. Further, we reported that curcumin targets IR-induced survival signaling and...

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Detalles Bibliográficos
Autores principales: Aravindan, Sheeja, Natarajan, Mohan, Awasthi, Vibhudutta, Herman, Terence S., Aravindan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743919/
https://www.ncbi.nlm.nih.gov/pubmed/23967300
http://dx.doi.org/10.1371/journal.pone.0072464