Co-segregation of hyperactivity, active coping styles, and cognitive dysfunction in mice selectively bred for low levels of anxiety

We established mouse models of extremes in trait anxiety, which are based on selective breeding for low vs. normal vs. high open-arm exploration on the elevated plus-maze. Genetically selected low anxiety-related behavior (LAB) coincided with hyperactivity in the home cage. Given the fact that sever...

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Detalles Bibliográficos
Autores principales: Yen, Yi-Chun, Anderzhanova, Elmira, Bunck, Mirjam, Schuller, Julia, Landgraf, Rainer, Wotjak, Carsten T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744008/
https://www.ncbi.nlm.nih.gov/pubmed/23966915
http://dx.doi.org/10.3389/fnbeh.2013.00103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744008/
https://www.ncbi.nlm.nih.gov/pubmed/23966915
http://dx.doi.org/10.3389/fnbeh.2013.00103

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