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An integrative computational analysis provides evidence for FBN1-associated network deregulation in trisomy 21

Although approximately 50% of Down Syndrome (DS) patients have heart abnormalities, they exhibit an overprotection against cardiac abnormalities related with the connective tissue, for example a lower risk of coronary artery disease. A recent study reported a case of a person affected by DS who carr...

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Detalles Bibliográficos
Autores principales: Vilardell, Mireia, Civit, Sergi, Herwig, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744068/
https://www.ncbi.nlm.nih.gov/pubmed/23951402
http://dx.doi.org/10.1242/bio.20134408