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Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures

Pseudoachondroplasia and multiple epiphyseal dysplasia are genetic skeletal diseases resulting from mutations in cartilage structural proteins. Electron microscopy and immunohistochemistry previously showed that the appearance of the cartilage extracellular matrix (ECM) in targeted mouse models of t...

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Detalles Bibliográficos
Autores principales: Bell, Peter A., Wagener, Raimund, Zaucke, Frank, Koch, Manuel, Selley, Julian, Warwood, Stacey, Knight, David, Boot-Handford, Raymond P., Thornton, David J., Briggs, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744072/
https://www.ncbi.nlm.nih.gov/pubmed/23951406
http://dx.doi.org/10.1242/bio.20135280