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Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures
Pseudoachondroplasia and multiple epiphyseal dysplasia are genetic skeletal diseases resulting from mutations in cartilage structural proteins. Electron microscopy and immunohistochemistry previously showed that the appearance of the cartilage extracellular matrix (ECM) in targeted mouse models of t...
Autores principales: | Bell, Peter A., Wagener, Raimund, Zaucke, Frank, Koch, Manuel, Selley, Julian, Warwood, Stacey, Knight, David, Boot-Handford, Raymond P., Thornton, David J., Briggs, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744072/ https://www.ncbi.nlm.nih.gov/pubmed/23951406 http://dx.doi.org/10.1242/bio.20135280 |
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