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Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have failed to translate to efficacious therapies for acute ischemic stroke(1). We hypothesized that studying the molecular determinants of endogenous neuroprotection in two well-e...

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Detalles Bibliográficos
Autores principales: Papadakis, Michalis, Hadley, Gina, Xilouri, Maria, Hoyte, Lisa C., Nagel, Simon, McMenamin, M Mary, Tsaknakis, Grigorios, Watt, Suzanne M., Drakesmith, Cynthia Wright, Chen, Ruoli, Wood, Matthew J A, Zhao, Zonghang, Kessler, Benedikt, Vekrellis, Kostas, Buchan, Alastair M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744134/
https://www.ncbi.nlm.nih.gov/pubmed/23435171
http://dx.doi.org/10.1038/nm.3097